There have to be a few main deaths in season 4. Of the following characters who do you think will die:
Rick Grimes
Carl Grimes
Daryl Dixon
Glenn Rhee
Maggie Greene/Rhee
Hershel Greene
Beth Greene
Carol Peletier
Michonne
Tyrese
Sasha
Bob Stookey
The Governor
Ceasar Martinez
Shumpert
Karen
In some behind the scenes pictures Rick has his hand wrapped up it is all still there though. But, in the trailer he does start to fight Tyrese maybe he broke his hand then.
There's rumors that Norman Reedus is trying to get Daryl into the comic book. Which if he does Merle will most likely be to. Of they agree to that they plan to have him live for a while.